Environmental Adaptation and Developmental Regulation
Revealed chromatin loop–mediated gene transcriptional regulation during vernalization.
Current Projects:
- Efficient Gene Transcription Regulation during Vernalization in Wheat Mediated By Chromatin Loops
- Epigenetic control on transcription of vernalization genes and whole-genome gene expression profile induced by vernalization in common wheat
Innovation and Application of Wheat Genomics and Genome Editing Tools
Focusing on leveraging advanced molecular biology techniques to enhance the efficiency and precision of wheat trait improvement through gene modification or optimization of experimental methods.
Current Projects:
- Overcoming genotypic dependency and bypassing immature embryos in wheat transformation by using morphogenic regulators
- CRISPR-Cereal: a guide RNA design tool integrating regulome and genomic variation for wheat, maize and rice
Improvement of Yield Traits and Grain Quality
This work integrates genomics and molecular biology approaches to unravel complex gene regulatory networks and epigenetic mechanisms, aiming to elucidate the molecular basis of key agronomic traits in wheat and provide guidance for molecular breeding.
Current Projects:
- Dynamic atlas of histone modifications and gene regulatory networks in endosperm of bread wheat
- Dissecting the molecular basis of spike traits by integrating gene regulatory network and genetic variation in wheat
